RSE on REM "Republican blood center" of the
Ministry of health of the Republic of Kazakhstan

Laboratory of Immunological Typing (HLA)

Amankulova Shamshiya Karakulova

Head of the Laboratory of Immunological Typing (HLA)

Education: Karaganda State Medical Institute, 2012-2017 with the first qualification category, in 2017 defended the highest category in clinical laboratory diagnostics.

С открытием лаботории, с 2015 по настоящее время является заведующей ЛИТ.

She has state and public awards:

  1. Award badge ”Excellent healthcare worker of the Republic of Kazakhstan";
  2. Award symbol “For contribution to healthcare”;
  3. The badge “For services to trade unions".

The Laboratory of Immunological Typing (HLA) is a structural subdivision of the Republican State Blood Center of the Ministry of Health of the Republic of Kazakhstan.

Main tasks of the laboratory:

  • Provision of all types of immunological research recipients and their donors for transplantation organizations organs (parts of an organ) and (or) tissues (parts of tissue);
  • Conducting immunological examination of recipients, on the Waiting List of the curated region;
  • Organization of collection of sera from recipients in need of transplantation of tissues (parts of tissues) and (or) organs (parts of organs) (hereinafter referred to as recipients);
  • Conducting HLA studies for immunological control of engraftment of transplanted organs and tissues.

Lab Functions:

In accordance with the assigned tasks, the laboratory performs the following functions:

  • Conducting HLA studies in recipients and donors in transplantation of kidneys and pancreas from an intravital and / or posthumous donor.
  • Conducting HLA studies in recipients and donors in transplantation of other organs (liver, heart and others) of an intravital and (or) posthumous donor.
  • HLA typing of recipients and donors in transplantation of hematopoietic stem cells (bone marrow) from related donors.
  • Conducting HLA studies in recipients included in the List expectations of the curated region.
  • Testing for compatibility "cross-match" between donor and recipient in organ transplantation.
  • Determination of donor chimerism in recipients after transplantation of hematopoietic stem cells (bone marrow).
  • Post-transplant monitoring of HLA antibodies in organ (tissue) transplant recipients.
  • Individual selection of platelets for recipients based on the HLA phenotype, if necessary.
  • Participation in the preparation of plans for professional development health workers on immunological tissue typing.
  • Organization of outreach work on clinical implications of immunological studies.
  • Submission of progress reports to the Central Laboratory.