RSE on REM "Republican blood center" of the
Ministry of health of the Republic of Kazakhstan

Immunological typing laboratory

  • Cross-Match compatibility test (by serological method) - determination of the compatibility of the donor with the recipient by serological method

  • loci HLA - A, B, DR by Flow fluorometry-molecular and genetic typing on 3 loci for organ transplantation

  • genotyping of blood according to the HLA system by SSP A / G loci of class I and II A B DRB1 low resolution molecular genetic typing at 3 loci for organ transplantation

  • determination of the presence of HLA antibodies by flow fluorometry to ensure readiness for selection of the recipient during cadaveric transplantation
  • determination of the presence of HLA antibodies of Class 1 and 2 in the blood serum by flow fluorometry - to determine the specificity of antibodies in order to predict the result of transplantation

  • determination of the percentage of serum sensitization by HLA-antibodies by Flow Cytometry - knowing the PRA% value for each recipient,you can navigate how easy it will be to choose a suitable donor for them. HLA antibodies have a very high specificity. PRA shows the percentage of potential donors with HLA antibodies in the recipient

  • blood genotyping by HLA system by SSP Class A / G loci I and II A B C DRB1 DQB1 low resolution typing by 5 LOCI to select a compatible donor during bone marrow and GJ transplantation< / li >
  • determination of the presence of HLA antibodies by Elisa-determination of the percentage of antibody sensitization in order to predict the result of transplantation

  • individual selection of blood components (platelets) based on the lymphocytotoxic test"Cross-Match" (serological method) - for recipients who did not have a clinical effect during previous platelet transfusions, platelets are selected individually

  • phenotyping of blood by serological method according to the HLA system (antigens of class I, loci a,b,c) low resolution-serological typing at Loci 3 of class I for organ transplantation

  • determination of genes of the histocompatible head complex by loci A B DRB1 DQB1 with division into haplotypes-to select a compatible donor for the recipient during GJ or bone marrow transplantation

  • detection of chimerism in patients after hematopoietic stem cell transplantation by capillary sequencing - to assess the suppression of transplantation after GJ or bone marrow transplantation.